Generation 3 PAMAM dendrimer TAMRA conjugates containing precise dye/dendrimer ratios
نویسندگان
چکیده
منابع مشابه
In Vitro Evaluation of Third Generation PAMAM Dendrimer Conjugates.
The present study compares the use of high generation G3 and low generation G0 Polyamidoamine (PAMAM) dendrimers as drug carriers of naproxen (NAP), a poorly water soluble drug. Naproxen was conjugated to G3 in different ratios and to G0 in a 1:1 ratio via a diethylene glycol linker. A lauroyl chain (L), a lipophilic permeability enhancer, was attached to G3 and G0 prodrugs. The G3 and G0 conju...
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PAMAM dendrimer-RGD-4C peptide conjugate was synthesized and in vitro targeting efficacy to integrin receptor expressing cells was studied by flow cytometry and confocal microscopy.
متن کاملDiffusion NMR Study of Generation-Five PAMAM Dendrimer Materials
Commercial generation-five poly(amidoamine) dendrimer material (G5c) was fractionated into its major structural components. Monomeric G5 (G5m; 21--30 kDa) was isolated to compare its functional properties to the G5c material. Diffusion-ordered nuclear magnetic resonance spectroscopy was employed to measure the self-diffusion coefficients and corresponding hydrodynamic radii of G5m and other G5c...
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We have evaluated the potential use of various polyamidoamine (PAMAM) dendrimer [dendrimer, generation (G) 2-4] conjugates with cyclodextrins (CyDs) as novel DNA and RNA carriers. Among the various dendrimer conjugates with CyDs, the dendrimer (G3) conjugate with α-CyD having an average degree of substitution (DS) of 2.4 [α-CDE (G3, DS2)] displayed remarkable properties as DNA, shRNA and siRNA ...
متن کاملusing generation 3 polyamidoamine dendrimer (pamam g3)as adsorbent for the removal of pentavalent arsenic fromaqueous solutions
introduction: arsenic is known as a carcinogenic compound in drinking water . it can cause acute and chronic effects on human health. in this study, the effect of polyamidoamine dendrimer generation 3(pamam g3) as adsorbents for removal of arsenic (v) from aqueous solutions was evaluated. methods: adsorption experiment was studied in batch system and the effect of different variables like p...
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ژورنال
عنوان ژورنال: Materials Today Communications
سال: 2015
ISSN: 2352-4928
DOI: 10.1016/j.mtcomm.2015.06.006